Forrest Simon

Single cell sequencing (SCS) technologies provide a level of resolution that makes it indispensable for inferring from a sequenced tumor, evolutionary trees or phylogenies representing an accumulation of cancerous mutations. A drawback of SCS is elevated false negative and missing value rates, resulting in a large space of possible solutions,…Read more

Among the 69.8% of patients discharged to the floor, and the 64.5% from the hospital, the scheduled nocturnal neuroactive medication was continued in 85.6% and 87.3%, respectively. Scheduled nocturnal neuroactive medication initiation is common, often continued beyond hospital discharge, and poorly documented.

We aimed to describe the…Read more

Expectant management in patients with prelabor preterm rupture of membranes between between 34

and 36

weeks (late preterm pPROM or LpPROM) has been shown to decrease the burden of prematurity, when compared to immediate delivery. As the severity of prematurity depends on gestational age (GA) at PROM, and PROM to delivery interval, we…Read more

on, persistent metformin compared with sulfonylurea use was associated with reduced heart failure hospitalization.Microtubules have been a concerning target of cancer chemotherapeutics for decades, and several tubulin-targeted agents, such as paclitaxel, vincristine and vinorelbine, have been approved. The colchicine binding site is one of the…Read more

7% in women, and 3.0% overall. Risk factors for this condition in both men and women included higher body mass index, diabetes, ethnicity (being other than Hispanic, non-Hispanic black, or non-Hispanic white), chronic obstructive pulmonary disease, coronary heart disease, and smoking.

This study established the criteria for low SHBG among…Read more

Based on the cross-reactivity between pollen lipid transfer proteins (LTPs) and the peach LTP, Pru p 3, it has been suggested that the pollen might initiate the LTP sensitization process.

To establish whether LTP allergy can be considered as a pollen-food syndrome.

The literature was reviewed and new data of component-resolved diagnosis…Read more

Water cycle in the soil-plant-atmosphere continuum (SPAC) is an important research topic in hydrology and ecology. The differences in the composition of hydrogen and oxygen stable isotopes in different water bodies can indicate water cycle process. Based on the measurements of isotopic compositions in precipitation, soil water, and plant water, we…Read more

To test the hypothesis that a culturally tailored sugar-sweetened beverage (SSB) campaign designed specifically for the Victorian Aboriginal community will not only be valuable for Aboriginal Victorians but will also have cross-over benefits for non-Aboriginal Victorians.

An online survey was completed by 155 Victorians (78 Aboriginal, 77…Read more

Follow-up was good (94% at 2 weeks). Only three participants used rescue antibiotics compared to 67% of acute diarrhoea patients in the hospital during the recruitment period. The median symptom duration was 14 h in group B (interquartile range (IQR) 10-22), 16 h in group D (IQR 10-22), 18 h in group A (IQR 10-33) and 20 h in group C (IQR 16-54).…Read more

Likewise, physical activity engagement reported positive associations with health-related quality of life, self-esteem, hours of nightly sleep, adherence to the Mediterranean diet and maximum oxygen uptake.

Interventions aimed at promoting physical activity must take into account these predictive factors, trying to favor their performance,…Read more

To develop a noninvasive prognostic imaging biomarker related to hypoxia to predict SABR tumor control.

A total of 145 subcutaneous syngeneic Dunning prostate R3327-AT1 rat tumors were focally irradiated once using cone beam computed tomography guidance on a small animal irradiator at 225 kV. Various doses in the range of 0 to 100 Gy were…Read more