Kessler Faircloth

Growing evidence suggests an association between parental longevity and lifespan of subsequent generations. We aimed to reproduce earlier findings, showing a positive association between parental longevity and offspring’s longevity. Additionally, we investigated whether this is mainly driven by the maternal or paternal germline in male and female…Read more

Moderate isometric handgrip exercise is an effective tool in the management of systemic hypertension.

To evaluate the effectiveness of a high intensity isometric handgrip exercise protocol for the reduction of blood pressure in older people with pre or stage-1 hypertension.

Twenty-three participants aged 73.8 ± 6.6 years (range…Read more

d Retail Food Environment Index score, 4-10 [adjusted odds ratio, 0.25; 95% confidence interval, 0.09-0.72] and modified Retail Food Environment Index score, ≥11 [adjusted odds ratio, 0.48; 95% confidence interval, 0.27-0.86]). There were no differences in the other secondary outcomes of interest.

The food environment affects the r…Read more

Surveillance of acute respiratory infections (ARI) in the Netherlands and other European countries is based mostly on primary care data, with little insight into the severe spectrum of the disease. We compared time-trends for ARI in secondary care with influenza-like illness (ILI), ARI and pneumonia in primary care, and crude mortality, in order…Read more

The improvement of the design and operation of energy conversion systems is a theme of global concern. As an energy intensive operation, industrial agricultural product drying has also attracted significant attention in recent years. Taking a novel industrial corn drying system with drying capacity of 5.5 t/h as a study case, based on existing…Read more

The comparative analysis of training of nursing staff in the territories of subjects of the Russian Federation, included in the Siberian Federal Okrug was implemented, based on data of the federal statistical monitoring of corresponding educational organizations in 2018. The analysis of calculated indices permitted to identify uncoordinated nature…Read more

Promoter methylation and microsatellite instability analysis found 95% and 97% concordance with clinical testing, respectively. We report the feasibility for amalgamation of the current stepwise and complex clinical testing workflow into an integrated test for hereditary and somatic causes of MMR deficiency.Bacterial vaginosis (BV) diagnosis in…Read more

Myrcludex B and Lonafarnib increase therapeutic efficacy in combination with Peg-IFN alfa. In a pilot study, REP 2139 in combination with Peg-IFN alfa induced the clearance of serum HDV RNA and of the HBsAg in about half of 12 treated patients. IMPLICATIONS Long-term therapies with either Myrcludex B or Lonafarnib in combination with Peg-IFN alfa…Read more

In addition, nanoparticles and CAR T cells were found on consecutive histopathological sections. Moreover, diffusion and perfusion MRI revealed significantly increased water diffusion and decreased vascular permeability on day 3 after treatment, which was simultaneously accompanied by a significant decrease in tumor cell proliferation and increase…Read more

The most common sites for WRMSDs were the upper back (48.19%), wrists/hands (44.27%), lower back (43.98%), neck (36.45%), and shoulder (33.43%). In most body parts, WRMSDs were more common among males and participants from a governmental university than among females or those from a private university.

Both dental students and dentists in…Read more

Ambulatory and not critically ill patients with COVID-19 treated with hydroxychloroquine, azithromycin and/or antiretrovirals develop a significant, but not relevant, QT interval prolongation.Abiotic and biotic stresses adversely affect plant growth and development and eventually result in less yield and threaten food security worldwide. In…Read more